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  5. GCLC Antibody (YA2898)

GCLC Antibody (YA2898)

Cat. No.: HY-P83153
User Guide for Antibodies Technical Support

GCLC Antibody (YA2898) is a biotin-conjugated non-conjugated IgG antibody, targeting GCLC, with a predicted molecular weight of 73 kDa (observed band size: 73 kDa). GCLC Antibody (YA2898) can be used for WB experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

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Description

GCLC Antibody (YA2898) is a biotin-conjugated non-conjugated IgG antibody, targeting GCLC, with a predicted molecular weight of 73 kDa (observed band size: 73 kDa). GCLC Antibody (YA2898) can be used for WB experiment in human, mouse, rat background.
Background

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The locus encodes the catalytic subunit, while the regulatory subunit is derived from a different related gene located on chromosome 1p22-p21. Mutations at The locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Gene ID

2729
Synonyms
GCLC; GLCL; GLCLC; Glutamate--cysteine ligase catalytic subunit; GCS heavy chain; Gamma-ECS; Gamma-glutamylcysteine synthetase
Molecular Weight

Predicted band size: 73 kDa; Observed band size: 73 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Signal Transduction
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human, Mouse, Rat
SwissProt ID

P48506
Dilution Ratio

WB: 1/500-1/1000
Application

WB
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

Recombinant protein of human GCLC
Documentation
User Guide for Antibodies (1077 KB)

GCLC Antibody (YA2898) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GCLC Antibody (YA2898)
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