Glutathione Peroxidase 2 Antibody (YA2153)

Glutathione Peroxidase 2 Antibody (YA2153) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2153), targeting Glutathione Peroxidase 2, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). Glutathione Peroxidase 2 Antibody (YA2153) can be used for WB, IHC-P experiment in human background.

The protein encoded by The related gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of The related gene family exist in vertebrates, which vary in cellular location and substrate specificity. The isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of The related gene is associated with increased differentiation and proliferation in colorectal cancer. The isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for The related gene.

2877

Predicted band size: 22 kDa; Observed band size: 22 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Cell Biology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P18283

WB: 1/500-1/1000;IHC: 1/50-1/100

WB, IHC-P

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Glutathione Peroxidase 2