GNE Antibody (YA2917)

GNE Antibody (YA2917) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2917), targeting GNE, with a predicted molecular weight of 79 kDa (observed band size: 75 kDa). GNE Antibody (YA2917) can be used for WB, IP experiment in human background.

The protein encoded by The related gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in The related gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of The related gene results in transcript variants encoding different isoforms.

10020

Predicted band size: 79 kDa; Observed band size: 75 kDa

Affinity Purified

Non-conjugated

Unmodified

Cardiovascular

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q9Y223

WB: 1/500-1/1000;IP: 1/20

WB, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human GLCNE