Granzyme B Antibody (YA1326)

Granzyme B Antibody (YA1326) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1326), targeting Granzyme B with observed band size of 32 kDa. Granzyme B Antibody (YA1326) can be used for WB, IP, ICC/IF, IHC-P experiment in human, mouse, rat background.

The related gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to related generate the active protease, which induces target cell apoptosis. The protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of The related gene may be elevated in human patients with cardiac fibrosis.

3002

Observed band size: 32 kDa

Affinity Purified

Non-conjugated

Unmodified

Immunology

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat

P10144

WB: 1:100-1:1,000;IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate);IF: 1:50-500;IHC-P: 1:50-500;

WB, IP, ICC/IF, IHC-P

Liquid

Supplied in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Endogenous

Amino acids 1-247 representing full length granzyme B of human origin.