HP1 alpha Antibody (YA983)

HP1 alpha Antibody (YA983) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA983), targeting HP1 alpha, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). HP1 alpha Antibody (YA983) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

The related gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The related gene has a pseudorelated gene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

23468

Predicted band size: 22 kDa; Observed band size: 22 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P45973

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human HP1 alpha