HP1 gamma Antibody (YA733)

HP1 gamma Antibody (YA733) is a non-conjugated and Mouse origined monoclonal antibody about 21 kDa, targeting to HP1 gamma (5G10). It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Mouse, Human, Monkey, Hamster, Rat.

HP1 gamma (5G10): At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

Free

11335

Predicted band size: 21 kDa

affinity purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Mouse, Human, Monkey, Hamster, Rat

Q13185

WB: 1:500-1:1,000 ;IHC: 1:50-1:100 ;IF: 1:50-1:200 ;IP: 1:20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG1

Endogenous

Synthetic peptide corresponding to Human HP1-gamma.The exact sequence is proprietary to MCE.