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  5. Human CD138 Antibody (PE)

Human CD138 Antibody (PE)

Cat. No.: HY-P83707m
User Guide for Antibodies

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

For research use only. We do not sell to patients.

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Description

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Gene ID

2833
Synonyms
CD_antigen antibody; CD138 antibody; CD138 antigen antibody; heparan sulfate proteoglycan fibroblast growth factor receptor antibody; SDC antibody; Sdc1 antibody; SDC1_HUMAN antibody; SYND1 antibody; Syndecan 1 antibody; Syndecan antibody; syndecan proteoglycan 1 antibody; Syndecan-1 antibody
Purity

Affinity
Conjugation

PE
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Reactivity

Human
SwissProt ID

P49682
Dilution Ratio

FC: 5μL per test for million cells or whole blood in 100 μL volume.
Application

FC
Appearance

Liquid
Formulation

Supplied in PBS、0.5%BSA、0.03%PC-300.
Storage & Stability

Stored at 2-8°C for 1 year, protect from light, do not freeze.
Shipping

Shipping with blue ice.
Isotype

IgG1
Immunogen

A synthesized peptide derived from Human CD183.
Documentation
User Guide for Antibodies (1077 KB)

Human CD138 Antibody (PE) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Human CD138 Antibody (PE)
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HY-P83707m
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