IGF2R Antibody (YA1499)

IGF2R Antibody (YA1499) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1499), targeting IGF2R, with a predicted molecular weight of 274 kDa (observed band size: 274 kDa). IGF2R Antibody (YA1499) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

The related gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. The receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of The related gene has been association with risk of hepatocellular carcinoma. The orthologous mouse related gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human related gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).

3482

Predicted band size: 274 kDa; Observed band size: 274 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Immunology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P11717

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/30;FC: 1/50-1/100

WB, IHC-P, ICC/IF, IP, FC

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human M6PR