Indoleamine 2,3-dioxygenase Antibody (YA3100)

Indoleamine 2,3-dioxygenase Antibody (YA3100) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3100), targeting Indoleamine 2,3-dioxygenase, with a predicted molecular weight of 45 kDa (observed band size: 45 kDa). Indoleamine 2,3-dioxygenase Antibody (YA3100) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

The related gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. The enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. The enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages The enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

3620

Predicted band size: 45 kDa; Observed band size: 45 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P14902

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human Indoleamine 2,3-dioxygenase