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  4. Leptin Antibody

Leptin Antibody

Cat. No.: HY-P81241
COA User Guide for Antibodies

Leptin Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Leptin, with a predicted molecular weight of 16 kDa . Leptin Antibody can be used for IHC-P, IHC-F, ICC/IF, ELISA experiments in human, mouse, rat, pig, sheep backgrounds.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $75 In-stock
50 μL $190 In-stock
100 μL $310 Get quote
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Leptin Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Leptin, with a predicted molecular weight of 16 kDa . Leptin Antibody can be used for IHC-P, IHC-F, ICC/IF, ELISA experiments in human, mouse, rat, pig, sheep backgrounds.

Background

The related gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. The protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiorelated genesis, reproduction, bone formation and wound healing. Mutations in The related gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in The related gene has also been linked to type 2 diabetes mellitus development.

Gene ID

3952

Synonyms
LEP; Leptin Murine Obesity Homolog; Leptin Precursor Obesity Factor; OB; Obese Protein; Obesity; Obesity factor; Obesity homolog mouse; Obesity Murine Homolog Leptin; OBS; LEP_HUMAN.
Molecular Weight

Predicted band size: 16 kDa

Purity

Affinity Purified

Subcellular Location

Secreted.

Conjugation

Non-conjugated

Modification

Unmodified

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat, Pig, Sheep

SwissProt ID

P41159

Dilution Ratio

WB: 1/500-2000; ELISA: 1/5000-10000; IHC-P: 1/100-500; IHC-F: 1/100-500; IF=1/100-500;

Application

IHC-P, IHC-F, ICC/IF, ELISA

Appearance

Liquid

Formulation

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

KLH conjugated synthetic peptide derived from human Leptin: 17-100/167

Documentation

Leptin Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Leptin Antibody
Cat. No.:
HY-P81241
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