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  4. Macro H2A.1 Antibody (YA3186)

Macro H2A.1 Antibody (YA3186)

Cat. No.: HY-P83441
User Guide for Antibodies Technical Support

Macro H2A.1 Antibody (YA3186) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3186), targeting Macro H2A.1, with a predicted molecular weight of 40 kDa (observed band size: 40 kDa). Macro H2A.1 Antibody (YA3186) can be used for WB, ICC/IF experiment in mouse, rat background.

For research use only. We do not sell to patients.

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Description

Macro H2A.1 Antibody (YA3186) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3186), targeting Macro H2A.1, with a predicted molecular weight of 40 kDa (observed band size: 40 kDa). Macro H2A.1 Antibody (YA3186) can be used for WB, ICC/IF experiment in mouse, rat background.

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The related gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID

9555

Synonyms
H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
Molecular Weight

Predicted band size: 40 kDa; Observed band size: 40 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Mouse, Rat

SwissProt ID

O75367

Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200

Application

WB, ICC/IF

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthetic peptide of human macroH2A.1

Documentation

Macro H2A.1 Antibody (YA3186) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Macro H2A.1 Antibody (YA3186)
Cat. No.:
HY-P83441
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