MCM3 Antibody (YA1137)

MCM3 Antibody (YA1137) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1137), targeting MCM3. MCM3 Antibody (YA1137) can be used for IHC-P experiment in human background.

The protein encoded by The related gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. The protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of The protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for The related gene.

4172

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P25205

IHC: 1/100-1/200

IHC-P

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.114.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human MCM3