MMP14 Antibody (YA1590)

MMP14 Antibody (YA1590) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1590), targeting MMP14, with a predicted molecular weight of 66 kDa (observed band size: 66 kDa). MMP14 Antibody (YA1590) can be used for WB, IHC-P, IP experiment in human, hamster background.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by The related gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of The subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The protein activates MMP2 protein, and The activity may be involved in tumor invasion.

4323

Predicted band size: 66 kDa; Observed band size: 66 kDa

Affinity Purified

Non-conjugated

Unmodified

Cardiovascular

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Hamster

P50281

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20

WB, IHC-P, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human MMP14