NF2 Antibody (YA1386)

NF2 Antibody (YA1386) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1386), targeting NF2, with a predicted molecular weight of 70 kDa (observed band size: 70 kDa). NF2 Antibody (YA1386) can be used for WB, IP experiment in human, mouse, rat background.

The related gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that link cytoskeletal components with proteins in the cell membrane. The encoded protein is involved in regulation of contact-dependent inhibition of cell proliferation and functions in cell-cell adhesion and transmembrane signaling. The encoded protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics, and proteins involved in regulating ion transport. Disruption of The protein's function has been implicated in tumorirelated genesis and metastasis. Mutations in The related gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities.

4771

Predicted band size: 70 kDa; Observed band size: 70 kDa

Affinity Purified

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P35240

WB: 1/500-1/1000;IP: 1/20

WB, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human NF2/Merlin