Nicotinic Acetylcholine Receptor alpha 4 Antibody (YA2616)

Nicotinic Acetylcholine Receptor alpha 4 Antibody (YA2616) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2616), targeting Nicotinic Acetylcholine Receptor alpha 4, with a predicted molecular weight of 70 kDa (observed band size: 70 kDa). Nicotinic Acetylcholine Receptor alpha 4 Antibody (YA2616) can be used for WB, IP experiment in human, mouse, rat background.

The related gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. The protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in The related gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in The related gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

1137

Predicted band size: 70 kDa; Observed band size: 70 kDa

Affinity Purified

Non-conjugated

Unmodified

-

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P43681

WB: 1/500-1/1000;IP: 1/50

WB, IP

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human ACHA4