PABPN1 Antibody (YA1521)

PABPN1 Antibody (YA1521) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1521), targeting PABPN1, with a predicted molecular weight of 33 kDa (observed band size: 50 kDa). PABPN1 Antibody (YA1521) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

The related gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, The protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. The related gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of The repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudorelated genes have been identified on chromosomes 19 and X. Read-through transcription also exists between The related gene and the neighboring upstream BCL2-like 2 (BCL2L2) related gene.

8106

Predicted band size: 33 kDa; Observed band size: 50 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

Q86U42

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human PABPN1