PEN2 Antibody (YA2118)

Cat. No.: HY-P82373: FAQs
Data Sheet User Guide for Antibodies

PEN2 Antibody (YA2118) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2118), targeting PEN2, with a predicted molecular weight of 12 kDa (observed band size: 12 kDa). PEN2 Antibody (YA2118) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size	Price	Stock
10 μL	$70	Ask For Quote & Lead Time
50 μL	$185	Ask For Quote & Lead Time
100 μL	$300	Ask For Quote & Lead Time

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Biological Activity
Technical Parameters
Properties
Documentation

Description	PEN2 Antibody (YA2118) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2118), targeting PEN2, with a predicted molecular weight of 12 kDa (observed band size: 12 kDa). PEN2 Antibody (YA2118) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
Background	Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein related generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. The related gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for The related gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants.
Gene ID	55851
Synonyms	PEN 2; PSEN2; psenen
Molecular Weight	Predicted band size: 12 kDa; Observed band size: 12 kDa
Purity	Affinity Chromatography
Conjugation	Non-conjugated
Modification	Unmodified
Research Field	Neuroscience
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	Q9NZ42
Dilution Ratio	WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100
Application	WB, IHC-P, ICC/IF, FC
Appearance	Liquid
Formulation	Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthesized peptide derived from human PEN2
Documentation	Data Sheet (235 KB) User Guide for Antibodies (1077 KB)

PEN2 Antibody (YA2118) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PEN2 Antibody (YA2118)

Biological Activity

Technical Parameters

Properties

Documentation

PEN2 Antibody (YA2118) Related Classifications

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