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  5. PHD2 Antibody (YA2431)

PHD2 Antibody (YA2431)

Cat. No.: HY-P82686
User Guide for Antibodies Technical Support

PHD2 Antibody (YA2431) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2431), targeting PHD2, with a predicted molecular weight of 46 kDa (observed band size: 46 kDa). PHD2 Antibody (YA2431) can be used for WB, IP experiment in human background.

For research use only. We do not sell to patients.

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Description

PHD2 Antibody (YA2431) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2431), targeting PHD2, with a predicted molecular weight of 46 kDa (observed band size: 46 kDa). PHD2 Antibody (YA2431) can be used for WB, IP experiment in human background.
Background

The protein encoded by The related gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. The protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in The related gene are associated with erythrocytosis familial type 3 (ECYT3).
Gene ID

54583
Synonyms
EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6; PHD2
Molecular Weight

Predicted band size: 46 kDa; Observed band size: 46 kDa
Purity

Affinity Chromatography
Conjugation

Non-conjugated
Modification

Unmodified
Research Field

Cardiovascular
Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality

Recombinant, Monoclonal
Host

Rabbit
Reactivity

Human
SwissProt ID

Q9GZT9
Dilution Ratio

WB: 1/500-1/1000;IP: 1/50
Application

WB, IP
Appearance

Liquid
Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

A synthesized peptide derived from human PHD2 / prolyl hydroxylase
Documentation
User Guide for Antibodies (1077 KB)

PHD2 Antibody (YA2431) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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