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  4. PHD2 Antibody (YA2431)

PHD2 Antibody (YA2431)

Cat. No.: HY-P82686
User Guide for Antibodies

PHD2 Antibody (YA2431) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2431), targeting PHD2, with a predicted molecular weight of 46 kDa (observed band size: 46 kDa). PHD2 Antibody (YA2431) can be used for WB, IP experiment in human background.

For research use only. We do not sell to patients.

Size Price Stock
10 μL $70 Ask For Quote & Lead Time
50 μL $185 Ask For Quote & Lead Time
100 μL $300 Ask For Quote & Lead Time

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PHD2 Antibody (YA2431) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2431), targeting PHD2, with a predicted molecular weight of 46 kDa (observed band size: 46 kDa). PHD2 Antibody (YA2431) can be used for WB, IP experiment in human background.

Background

The protein encoded by The related gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. The protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in The related gene are associated with erythrocytosis familial type 3 (ECYT3).

Gene ID

54583

Synonyms
EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6; PHD2
Molecular Weight

Predicted band size: 46 kDa; Observed band size: 46 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cardiovascular

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human

SwissProt ID

Q9GZT9

Dilution Ratio

WB: 1/500-1/1000;IP: 1/50

Application

WB, IP

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human PHD2 / prolyl hydroxylase

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PHD2 Antibody (YA2431)
Cat. No.:
HY-P82686
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