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  4. Phospho-c-Myc (Ser62) Antibody

Phospho-c-Myc (Ser62) Antibody

Cat. No.: HY-P80804
COA User Guide for Antibodies

Phospho-c-Myc (Ser62) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 49 kDa, targeting to Phospho-c-Myc (Ser62). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-c-Myc (Ser62) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 49 kDa, targeting to Phospho-c-Myc (Ser62). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Mouse, Rat.

Background

c-Myc: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Tag

Free

Gene ID

4609

Synonyms
MYC; BHLHE39; Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
Molecular Weight

Predicted band size: 49 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Phosphorylated

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Mouse, Rat

SwissProt ID

P01106

Dilution Ratio

WB: 1:500-1:1,000 ;IF: 1:50-1:200 ;IP: 1:20

Application

WB, ICC/IF, IP

Appearance

Liquid

Formulation

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Ser62 of Human c-Myc.The exact sequence is proprietary to MCE.

Documentation

Phospho-c-Myc (Ser62) Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phospho-c-Myc (Ser62) Antibody
Cat. No.:
HY-P80804
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