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  4. Phospho-Histone H2A.X (Ser139) Antibody (YA191)

Phospho-Histone H2A.X (Ser139) Antibody (YA191)

Cat. No.: HY-P80821
COA User Guide for Antibodies

Phospho-Histone H2A.X (Ser139) Antibody (YA191) is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Phospho-Histone H2A.X (Ser139). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-Histone H2A.X (Ser139) Antibody (YA191) is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Phospho-Histone H2A.X (Ser139). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

Background

Histone H2A.X: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]

Tag

Free

Gene ID

3014

Synonyms
H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X
Molecular Weight

Predicted band size: 15 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Phosphorylated

Research Field

Epigenetics and Nuclear Signaling

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P16104

Dilution Ratio

WB: 1:500-1:1,000 ;IP: 1:20

Application

WB, IP

Appearance

Liquid

Formulation

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Ser139 of Human gamma H2A.X.The exact sequence is proprietary to MCE.

Documentation

Phospho-Histone H2A.X (Ser139) Antibody (YA191) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phospho-Histone H2A.X (Ser139) Antibody (YA191)
Cat. No.:
HY-P80821
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