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  4. Phospho-IRE1 (Ser724) Antibody

Phospho-IRE1 (Ser724) Antibody

Cat. No.: HY-P80828
Data Sheet SDS COA User Guide for Antibodies Technical Support

Phospho-IRE1 (Ser724) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 110 kDa, targeting to Phospho-IRE1 (Ser724). It can be used for WB,IP assays with tag free, in the background of Human.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL USD 70 In-stock
50 μL USD 185 In-stock
100 μL USD 300 In-stock
250 μL   Get quote  

Get it by April 15 for select sizes. Order within 2 hrs 6 mins.

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  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Phospho-IRE1 (Ser724) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 110 kDa, targeting to Phospho-IRE1 (Ser724). It can be used for WB,IP assays with tag free, in the background of Human.

Background

IRE1: This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. [provided by RefSeq, Aug 2017]

Tag

Free

Gene ID

2081

Synonyms
ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
Molecular Weight

Predicted band size: 110 kDa

Purity

affinity purified

Conjugation

Non-conjugated

Modification

Phosphorylated

Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human

SwissProt ID

O75460

Dilution Ratio

WB: 1:500-1:1,000 ;IP: 1:20

Application

WB, IP

Appearance

Liquid

Formulation

Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Ser724 of Human IRE1.The exact sequence is proprietary to MCE.

Documentation

Phospho-IRE1 (Ser724) Antibody Related Classifications

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Product Name:
Phospho-IRE1 (Ser724) Antibody
Cat. No.:
HY-P80828
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