Phospho-Nucleophosmin (Thr199) Antibody (YA2622)

Phospho-Nucleophosmin (Thr199) Antibody (YA2622) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2622), targeting Phospho-Nucleophosmin (Thr199), with a predicted molecular weight of 33 kDa (observed band size: 38 kDa). Phospho-Nucleophosmin (Thr199) Antibody (YA2622) can be used for WB, IHC-P, IP experiment in human, rat background.

The protein encoded by The related gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. The protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in The related gene are associated with acute myeloid leukemia. Dozens of pseudorelated genes of The related gene have been identified.

4869

Predicted band size: 33 kDa; Observed band size: 38 kDa

Affinity Purified

Non-conjugated

Phosphorylated

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Rat

P06748

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20

WB, IHC-P, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic phosphopeptide corresponding to residues surrounding Thr199 of human Nucleophosmin