Phospho-Phospholamban (Ser16) Antibody (YA1618)

Phospho-Phospholamban (Ser16) Antibody (YA1618) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospho-Phospholamban (Ser16), with a predicted molecular weight of 6 kDa (observed band size: 12,24 kDa). Phospho-Phospholamban (Ser16) Antibody (YA1618) can be used for WB experiment in human, mouse background.

The protein encoded by The related gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in The related gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.

5350

Predicted band size: 6 kDa; Observed band size: 12,24 kDa

Affinity Purified

Non-conjugated

Phosphorylated

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

P26678

WB: 1/500-1/1000

WB

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic phosphopeptide corresponding to residues surrounding Ser16 of human Phospholamban