Phospho-PKC alpha (Thr638) Antibody (YA1024)

Phospho-PKC alpha (Thr638) Antibody (YA1024) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1024), targeting Phospho-PKC alpha (Thr638), with a predicted molecular weight of 77 kDa (observed band size: 80 kDa). Phospho-PKC alpha (Thr638) Antibody (YA1024) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by The related gene is one of the PKC family members. The kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that The kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

5578

Predicted band size: 77 kDa; Observed band size: 80 kDa

Affinity Purified

Non-conjugated

Phosphorylated

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P17252

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20

WB, IHC-P, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic phosphopeptide corresponding to residues surrounding Thr638 of human PKC alpha