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  5. Phospho-PKM2(Tyr105)Antibody

Phospho-PKM2(Tyr105)Antibody

Cat. No.: HY-P83644
COA User Guide for Antibodies

Phospho-PKM2(Tyr105)Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Phospho-PKM2(Tyr105)Antibody, with a predicted molecular weight of 58 kDa. Phospho-PKM2(Tyr105)Antibody can be used for IHC-P, IHC-F, ICC/IF, FC, ELISA experiments in human, rat backgrounds.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $75 In-stock
50 μL $200 In-stock
100 μL $325 In-stock
250 μL   Get quote  
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Description

Phospho-PKM2(Tyr105)Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Phospho-PKM2(Tyr105)Antibody, with a predicted molecular weight of 58 kDa. Phospho-PKM2(Tyr105)Antibody can be used for IHC-P, IHC-F, ICC/IF, FC, ELISA experiments in human, rat backgrounds.
Background

The related gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, related generating ATP and pyruvate. The protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. The protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of The protein in bacterial pathorelated genesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Gene ID

5315
Synonyms
PKM2 (Phospho Tyr105); PKM2 (Phospho Y105); PK 1; PK 2; PK 3; PK Muscle type; PK1; PK2; Pk3; PKL; PKLR; PKM 2; PKM; PYKM; Pyruvate kinase 1; Pyruvate kinase 2/3; Pyruvate kinase 3; Pyruvate kinase isozyme R/L; Pyruvate kinase isozymes M1/M2; Pyruvate kinase liver and blood cell; Pyruvate kinase liver and RBC; Pyruvate kinase liver and RBC type; Pyruvate kinase M2; Pyruvate kinase muscle; Pyruvate kinase muscle isozyme; Pyruvate kinase type L; R type/L type pyruvate kinase; Red cell/liver pyruvate kinase; RPK; TCB; THBP 1; THBP1; Thyroid hormone binding protein cytosolic; CTHBP; Cytosolic thyroid hormone binding protein; MGC3932; OIP 3; Oip3; Tumor M2-PK; p58; OIP-3.
Molecular Weight

Predicted band size: 58 kDa
Purity

Affinity Purified
Conjugation

Non-conjugated
Modification

Phosphorylated
Product Categories

Primary Antibody; Rabbit Polyclonal Antibody
Clonality

Polyclonal
Host

Rabbit
Reactivity

Human, Rat
Predicted Reactivity

Mouse, Dog, Pig, Cow, Horse, Rabbit, GuineaPig

Note: The predicted reactivity is for reference only, not as a product performance guarantee.
SwissProt ID

P14618
Dilution Ratio

IHC-P: 1:100-500;IHC-F: 1:100-500;IF: 1:100-500;Flow-Cyt: 1ug/Test;ELISA: 1:5000-10000
Application

IHC-P, IHC-F, ICC/IF, FC, ELISA
Appearance

Liquid
Formulation

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG
Sensitivity

Endogenous
Immunogen

KLH conjugated Synthesised phosphopeptide derived from human PKM2 around the phosphorylation site of Tyr105: IL(p-Y)RP

Documentation

COA (191 KB)

User Guide for Antibodies (1077 KB)

Phospho-PKM2(Tyr105)Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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