PIN1 Antibody (YA1635)

PIN1 Antibody (YA1635) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1635), targeting PIN1, with a predicted molecular weight of 18 kDa (observed band size: 18 kDa). PIN1 Antibody (YA1635) can be used for WB, ICC/IF experiment in human, mouse, rat background.

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. The related gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by The PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. The enzyme also plays a key role in the pathorelated genesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for The related gene.

5300

Predicted band size: 18 kDa; Observed band size: 18 kDa

Affinity Purified

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q13526

WB: 1/500-1/1000;IF: 1/50-1/200

WB, ICC/IF

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Pin1