PSGL1 Antibody (YA1456)

PSGL1 Antibody (YA1456) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1456), targeting PSGL1, with a predicted molecular weight of 43 kDa (observed band size: 120 kDa). PSGL1 Antibody (YA1456) can be used for WB, IHC-P, ICC/IF, IP experiment in human background.

The related gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, The protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. The protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of The related gene and polymorphisms in The related gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

6404

Predicted band size: 43 kDa; Observed band size: 120 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Immunology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q14242

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/40

WB, IHC-P, ICC/IF, IP

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human CD162