Rad23B Antibody (YA1075)

Rad23B Antibody (YA1075) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA1075), targeting Rad23B, with a predicted molecular weight of 43 kDa (observed band size: 58 kDa). Rad23B Antibody (YA1075) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat, monkey, hamster background.

The protein encoded by The related gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). The protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. The protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. The protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus The protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

5887

Predicted band size: 43 kDa; Observed band size: 58 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Mouse Monoclonal Antibody

Monoclonal

Mouse

Human, Mouse, Rat, Monkey, Hamster

P54727

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200

WB, IHC-F, IHC-P, ICC/IF

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG2b

Endogenous

Purified recombinant human hHR23b protein fragments expressed in E.coli.