Rad50 Antibody (YA1681)

Rad50 Antibody (YA1681) is a biotin-conjugated non-conjugated IgG antibody, targeting Rad50, with a predicted molecular weight of 154 kDa (observed band size: 154 kDa). Rad50 Antibody (YA1681) can be used for WB experiment in human background.

The protein encoded by The related gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. The protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. The protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest The related gene is essential for cell growth and viability. Mutations in The related gene are the cause of Nijmegen breakage syndrome-like disorder.

10111

Predicted band size: 154 kDa; Observed band size: 154 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

Q92878

WB: 1/500-1/1000

WB

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Rad50