RASGRP1 Antibody (YA2546)

RASGRP1 Antibody (YA2546) is a biotin-conjugated non-conjugated IgG antibody, targeting RASGRP1, with a predicted molecular weight of 90 kDa (observed band size: 90 kDa). RASGRP1 Antibody (YA2546) can be used for WB experiment in human background.

The related gene is a member of a family of related genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of The protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).

10125

Predicted band size: 90 kDa; Observed band size: 90 kDa

Affinity Purified

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

O95267

WB: 1/500-1/1000

WB

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Rasgrp1