Sarcomeric alpha Actinin Antibody (YA1903)

Sarcomeric alpha Actinin Antibody (YA1903) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1903), targeting Sarcomeric alpha Actinin, with a predicted molecular weight of 104 kDa (observed band size: 104 kDa). Sarcomeric alpha Actinin Antibody (YA1903) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

Alpha actinins belong to the spectrin related gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. The related gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for The related gene.

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Predicted band size: 104 kDa; Observed band size: 104 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P35609

WB: 1/500-1/1000;IHC: 1/50-1/100;IP: 1/20

WB, IHC-P, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Sarcomeric Alpha Actinin