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  4. SH2D1A Antibody (YA1950)

SH2D1A Antibody (YA1950)

Cat. No.: HY-P82205
COA User Guide for Antibodies

SH2D1A Antibody (YA1950) is a biotin-conjugated non-conjugated IgG antibody, targeting SH2D1A, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). SH2D1A Antibody (YA1950) can be used for WB experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $75 In-stock
50 μL $190 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

SH2D1A Antibody (YA1950) is a biotin-conjugated non-conjugated IgG antibody, targeting SH2D1A, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). SH2D1A Antibody (YA1950) can be used for WB experiment in human, mouse, rat background.

Background

The related gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. The protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of The transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. The protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in The related gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for The related gene.

Gene ID

4068

Synonyms
LYP; SAP; XLP; DSHP; EBVS; IMD5; XLPD; MTCP1; XLPD1; SAP/SH2D1A
Molecular Weight

Predicted band size: 14 kDa; Observed band size: 14 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Cardiovascular

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

O60880

Dilution Ratio

WB: 1/500-1/1000

Application

WB

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthetic peptide of human SH2D1A/SAP

Documentation

SH2D1A Antibody (YA1950) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SH2D1A Antibody (YA1950)
Cat. No.:
HY-P82205
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