SLC12A1 Antibody (YA3471)

SLC12A1 Antibody (YA3471) is a non-conjugated IgG antibody, targeting SLC12A1, with a predicted molecular weight of 121 kDa (observed band size: 150 kDa). SLC12A1 Antibody (YA3471) can be used for WB, IHC-P, IF-Cell, mIHC experiment in human, Mouse and Rat background.

The related gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in The related gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

6557

Predicted band size: 121 kDa; Observed band size: 150 kDa

Affinity Purified

Cell membrane

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal, Recombinant

Rabbit

Human, Mouse, Rat

Q13621

WB: 1:2,000;IHC-P: 1:20,000;IF-Cell: 1:100;mIHC: 1:3,000

WB, IHC-P, ICC/IF

Mouse kidney tissue lysate, rat kidney tissue lysate, K-562 cell lysate, mouse kidney tissue, K-562.

Liquid

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Recombinant protein within Human SLC12A1 / NKCC2 aa 593-813 / 1,099.