Stromal Interaction Molecule 1 Antibody (YA2092)

Stromal Interaction Molecule 1 Antibody (YA2092) is a biotin-conjugated non-conjugated IgG antibody, targeting Stromal Interaction Molecule 1, with a predicted molecular weight of 77 kDa (observed band size: 77 kDa). Stromal Interaction Molecule 1 Antibody (YA2092) can be used for WB experiment in human, mouse, rat background.

The related gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several related genes located in the imprinted related gene domain of 11p15.5, an important tumor-suppressor related gene region. Alterations in The region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. The related gene may play a role in malignancies and disease that involve The region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in The related gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. The related gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 related gene (RRM1), with the 3' end of The related gene situated 1.6 kb from the 5' end of the RRM1 related gene. Alternative splicing of The related gene results in multiple transcript variants.

6786

Predicted band size: 77 kDa; Observed band size: 77 kDa

Affinity Purified

Non-conjugated

Unmodified

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q13586

WB: 1/500-1/1000

WB

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human Stromal interaction molecule 1