Syntrophin alpha 1 Antibody (YA1828)

Syntrophin alpha 1 Antibody (YA1828) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1828), targeting Syntrophin alpha 1, with a predicted molecular weight of 54 kDa (observed band size: 54 kDa). Syntrophin alpha 1 Antibody (YA1828) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse background.

Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. The related gene is a member of the syntrophin related gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of The syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. The protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. The related gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). The protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue.

6640

Predicted band size: 54 kDa; Observed band size: 54 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

Q13424

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;FC: 1/50-1/100

WB, IHC-P, ICC/IF, FC

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Syntrophin alpha 1