TGF beta Receptor II Antibody

TGF beta Receptor II Antibody is an unconjugated, approximately 65 kDa, rabbit-derived, anti-TGF beta Receptor II polyclonal antibody. TGF beta Receptor II Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, cow, and predicted: chicken, pig, horse, rabbit, sheep background without labeling.

The protein encoded by The related gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. The receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of related genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorirelated genesis. Mutations in The related gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

7048

Predicted band size: 65kDa；Observed band size: 65 kDa

affinity purified

Cell membrane; Single-pass type I membrane protein.

Non-conjugated

Unmodified

Primary Antibody; Rabbit Polyclonal Antibody

Polyclonal

Rabbit

Human, Mouse, Rat

P37173

WB: 1:500-2000;IHC: 1:50-100;IF: 1:50-200;ELISA: 1:5000-10000

WB, ELISA, IHC-P, IHC-F, ICC/IF

Liquid

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

KLH conjugated synthetic peptide derived from human TGF beta Receptor II: 241-330/567