TIRAP Antibody (YA2589)

TIRAP Antibody (YA2589) is a non-conjugated IgG antibody, targeting TIRAP, with a predicted molecular weight of 24 kDa (observed band size: 28 kDa). TIRAP Antibody (YA2589) can be used for WB experiment in human, mouse, rat background.

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by The related gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of The related gene results in several transcript variants; however, not all variants have been fully described.

114609

Predicted band size: 24 kDa; Observed band size: 28 kDa

Affinity Purified

Non-conjugated

Unmodified

Immunology

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P58753

WB: 1/500-1/1000

WB

Liquid

Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human TIRAP