TLR2 Antibody

TLR2 Antibody is an unconjugated, approximately 84 kDa, rabbit-derived, anti-TLR2 monoclonal antibody. TLR2 Antibody can be used for: WB, FC, IF-Cell expriments in human, mouse, rat background without labeling.

The protein encoded by The related gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. The protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. The related gene is also thought to promote apoptosis in response to bacterial lipoproteins. The related gene has been implicated in the pathorelated genesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.

7097

Predicted band size: 84kDa

affinity purified

Membrane; Single-pass type I membrane protein.

Non-conjugated

Unmodified

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Monoclonal, Recombinant

Rabbit

Human, Mouse, Rat

O60603

WB: 1:500-1:2,000; FC: 1:50-1:100; IF-Cell: 1:50-1:100;

WB, ICC/IF, FC

Liquid

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein within human TLR2 aa 21-588 (Extracellular).