Tropomyosin alpha 1 Chain Antibody (YA2183)

Tropomyosin alpha 1 Chain Antibody (YA2183) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2183), targeting Tropomyosin alpha 1 Chain, with a predicted molecular weight of 33 kDa (observed band size: 33 kDa). Tropomyosin alpha 1 Chain Antibody (YA2183) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

The related gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in The related gene are associated with type 3 familial hypertrophic cardiomyopathy and dilated cardiomyopathy 1Y.

7168

Predicted band size: 33 kDa; Observed band size: 33 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

P09493

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100

WB, IHC-P, ICC/IF, IP, FC

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Tropomyosin 1