Ubiquitin Protein Ligase E3A Antibody (YA3306)

Ubiquitin Protein Ligase E3A Antibody (YA3306) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3306), targeting Ubiquitin Protein Ligase E3A, with a predicted molecular weight of 101 kDa (observed band size: 101 kDa). Ubiquitin Protein Ligase E3A Antibody (YA3306) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

The related gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. The imprinted related gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of The related gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of The related gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.

7337

Predicted band size: 101 kDa; Observed band size: 101 kDa

Affinity Purified

Non-conjugated

Unmodified

Epigenetics and Nuclear Signaling

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q05086

WB: 1/500-1/1000;IF: 1/50-1/200;IP: 1/20

WB, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

Recombinant protein of human UBE3A