1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies Recombinant Antibodies
  4. uPA Antibody (YA3248)

uPA Antibody (YA3248)

Cat. No.: HY-P83503
COA User Guide for Antibodies

uPA Antibody (YA3248) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3248), targeting uPA, with a predicted molecular weight of 49 kDa (observed band size: 49 kDa). uPA Antibody (YA3248) can be used for WB, IHC-P experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

uPA Antibody (YA3248) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3248), targeting uPA, with a predicted molecular weight of 49 kDa (observed band size: 49 kDa). uPA Antibody (YA3248) can be used for WB, IHC-P experiment in human, mouse, rat background.

Background

The related gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to related generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). The low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in The related gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Gene ID

5328

Synonyms
Urokinase-type plasminogen activator; U-plasminogen activator; Upa; PLAU; ATF uPA
Molecular Weight

Predicted band size: 49 kDa; Observed band size: 49 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Neuroscience

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P00749

Dilution Ratio

WB: 1/500-1/1000;IHC: 1/50-1/100

Application

WB, IHC-P

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Urokinase

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
uPA Antibody (YA3248)
Cat. No.:
HY-P83503
Quantity:
MCE Japan Authorized Agent: