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  4. VAV1 Antibody (YA2161)

VAV1 Antibody (YA2161)

Cat. No.: HY-P82416
COA User Guide for Antibodies

VAV1 Antibody (YA2161) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2161), targeting VAV1, with a predicted molecular weight of 98 kDa (observed band size: 98 kDa). VAV1 Antibody (YA2161) can be used for WB, ICC/IF, IP, FC experiment in human background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

VAV1 Antibody (YA2161) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2161), targeting VAV1, with a predicted molecular weight of 98 kDa (observed band size: 98 kDa). VAV1 Antibody (YA2161) can be used for WB, ICC/IF, IP, FC experiment in human background.

Background

The related gene is a member of the VAV related gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for The related gene.

Gene ID

7409

Synonyms
p95; p95vav; Protein vav 1; Protein vav 2; Protein vav 3; VAV; vav-T
Molecular Weight

Predicted band size: 98 kDa; Observed band size: 98 kDa

Purity

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Signal Transduction

Product Categories

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Clonality

Recombinant, Monoclonal

Host

Rabbit

Reactivity

Human

SwissProt ID

P15498

Dilution Ratio

WB: 1/500-1/1000;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100

Application

WB, ICC/IF, IP, FC

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

A synthesized peptide derived from human Vav1/2/3

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
VAV1 Antibody (YA2161)
Cat. No.:
HY-P82416
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