VAV1 Antibody (YA2161)

VAV1 Antibody (YA2161) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2161), targeting VAV1, with a predicted molecular weight of 98 kDa (observed band size: 98 kDa). VAV1 Antibody (YA2161) can be used for WB, ICC/IF, IP, FC experiment in human background.

The related gene is a member of the VAV related gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for The related gene.

7409

Predicted band size: 98 kDa; Observed band size: 98 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human

P15498

WB: 1/500-1/1000;IF: 1/50-1/200;IP: 1/50;FC: 1/50-1/100

WB, ICC/IF, IP, FC

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human Vav1/2/3