Vitamin D Receptor Antibody

Vitamin D Receptor Antibody is an unconjugated, approximately 47 kDa, rabbit-derived, anti-Vitamin D Receptor polyclonal antibody. Vitamin D Receptor Antibody can be used for: IHC-P, IHC-F, ICC, IF expriments in human, rat, and predicted: mouse, chicken, pig, cow, horse, rabbit background without labeling.

The related gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. The receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though The receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in The related gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for The related gene. A recent study provided evidence for translational readthrough in The related gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

7421

Predicted band size: 47kDa

affinity purified

Nucleus.

Non-conjugated

Unmodified

Primary Antibody; Rabbit Polyclonal Antibody

Polyclonal

Rabbit

Human, Rat

Mouse, Chicken, Pig, Cow, Horse, Rabbit

P11473

IHC-P: 1:100-500;IHC-F: 1:100-500;ICC: 1:100;IF: 1:100-500

IHC-P, IHC-F, ICC/IF

Liquid

Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

KLH conjugated synthetic peptide derived from human Vitamin D Receptor: 65-180/427