2. Immunology/Inflammation Apoptosis NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species Apoptosis
  4. Anticancer agent 175

Anticancer agent 175 (complex 1) ia a near-infrared (NIR) luminescent theranostic complex. Anticancer agent 175 induces ROS accumulation, mitochondrial damage, disruption of Bax/Bcl-2 equilibrium, and tumor cell apoptosis in HepG2 cell line.

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Anticancer agent 175 Chemical Structure

Anticancer agent 175 Chemical Structure

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Description

Anticancer agent 175 (complex 1) ia a near-infrared (NIR) luminescent theranostic complex. Anticancer agent 175 induces ROS accumulation, mitochondrial damage, disruption of Bax/Bcl-2 equilibrium, and tumor cell apoptosis in HepG2 cell line[1].

Molecular Weight

1648.78

Formula

C81H86F10IrN8O4P-
SMILES

CC1=C2C3=CC=CC=C3[Ir]45([N]6=C7C=C(F)C(F)=CC7=NC(C)=C6C8=CC=CC=C84)([N]9=C%10C=CC=CC%10=C(C(NCCCCCCNC([C@@](C)(CC[C@@]%11(CC[C@@]%12(C%13=CC([C@@]%14([C@]%15(CC[C@@H](C([C@@]%15(CC[C@@]%12%14C)[H])(C)C)O)C)[H])=O)C)C)C[C@]%11%13[H])=O)=O)C=C9C%16=CC=CC=[N]%165)[N]2=C%17C=C(F)C(F)=CC%17=N1.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
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Room temperature in continental US; may vary elsewhere.
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Anticancer agent 175 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 175Anticancer agent175Anticancer agent-175Reactive Oxygen SpeciesApoptosisHepatocellular carcinomaHepG2apoptosisROSInhibitorinhibitorinhibit

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