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  3. Anticancer agent 213

Anticancer agent 213 (Compound 1) exhibits anticancer efficacy by self-assembling into micelles, depleting membran cholesterol and thus inhibiting cancer cells. Anticancer agent 213 exhibits cytotoxicity against HeLa and PC3, with IC50 of 10.3 and 13.7 μM. Anticancer agent 213 induces autophagy.

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Anticancer agent 213 Chemical Structure

Anticancer agent 213 Chemical Structure

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Description

Anticancer agent 213 (Compound 1) exhibits anticancer efficacy by self-assembling into micelles, depleting membran cholesterol and thus inhibiting cancer cells. Anticancer agent 213 exhibits cytotoxicity against HeLa and PC3, with IC50 of 10.3 and 13.7 μM. Anticancer agent 213 induces autophagy[1].

Molecular Weight

669.73

Formula

C38H35N7O5

SMILES

N[C@@H](C(N[C@@H](C(NCCNC1=CC=C(C2=NON=C12)[N+]([O-])=O)=O)CC3=CC=C(C=C3)C4=CC=CC=C4)=O)CC5=CC=C(C=C5)C6=CC=CC=C6

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Room temperature in continental US; may vary elsewhere.

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Anticancer agent 213 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anticancer agent 213
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HY-158373
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