2. GPCR/G Protein
  3. GnRH Receptor
  4. Antide acetate

Antide acetate  (Synonyms: D-21074 acetate; ORF 23541 acetate)

Cat. No.: HY-P0013A
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Antide (D-21074) acetate is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer.

For research use only. We do not sell to patients.

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Antide acetate Chemical Structure

Antide acetate Chemical Structure

CAS No. : 625092-10-6

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Antide acetate Related Antibodies

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Description

Antide (D-21074) acetate is a potent LHRH antagonist. Antide also can be used for the research of prostatic cancer[1].

In Vivo

Antide (subcutaneously; 1, 3, 6, 10 and 15 mg/kg; once or on 5 consecutive days) can induce a long-term chemical castration in adult male rats and cynomolgus monkeys[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cynomolgus monkey and rat[1]
Dosage: 1, 3, 6, 10 and 15 mg/kg
Administration: Subcutaneous, once or on 5 consecutive days
Result: Had a dose-dependent inhibitory effect on serum concentration of LH (only rat) and testosterone and on the weights of the testes, prostates and seminal vesicles.
Achieved long-lasting castration-like effects at concentrations between 6 (less than or equal to 8 weeks) and 15 mg/kg (greater than 8 weeks) in the rat.
Induced a prolonged inhibitory effect only at 15 mg/kg and the duration was only 2-3 weeks in the cynomolgus monkey.
Molecular Weight

1651.35

Formula

C84H112ClN17O16
CAS No.
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antide acetate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antide625092-10-6D-21074ORF 23541D21074D 21074ORF23541ORF-23541GnRH ReceptorGonadotropin releasing hormone receptorGNRHRLHRHprostatic cancercynomolgus monkeyratInhibitorinhibitorinhibit

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