2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Antidepressant agent 6

Antidepressant agent 6 (S-3a) is a lead compound with potent and sustained antidepressant effects. Antidepressant agent 6 (S-3a) displays high cognitive safety margin.Antidepressant agent 6 (S-3a) antagonizes M1 receptors and elevates BDNF levels, suggesting its potential as an antidepressant for further exploration.

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Antidepressant agent 6 Chemical Structure

Antidepressant agent 6 Chemical Structure

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Antidepressant agent 6 Related Antibodies

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Description

Antidepressant agent 6 (S-3a) is a lead compound with potent and sustained antidepressant effects. Antidepressant agent 6 (S-3a) displays high cognitive safety margin.Antidepressant agent 6 (S-3a) antagonizes M1 receptors and elevates BDNF levels, suggesting its potential as an antidepressant for further exploration[1].
In Vivo

Antidepressant agent 6 (S-3a) alleviates depressive symptoms in mice and displayes a higher cognitive safety margin than scopolamine[1].
Antidepressant agent 6 (S-3a) alleviates despair behavior in CRS mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Reserpine-Induced Depression Model in Mice[1].
Dosage: 25, 100, or 300 μg/kg.
Administration: Administered intraperitoneally every other day.
Result: Did not cause changes in total distance during the OFT, suggesting its antidepressant-like effects were independent of locomotor activity.
Could alleviate depression-induced weight loss relative to the untreated model group.
Molecular Weight

321.34

Formula

C17H20FNO4
SMILES

CN1[C@@H]2CC(C[C@H]1[C@@H]3O[C@@H]32)OC([C@@](CO)(C4=CC=CC=C4)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antidepressant agent 6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antidepressant agent 6Antidepressant agent6Antidepressant agent-6mAChRMuscarinic acetylcholine receptordepressionBNDFCRSM1 receptorInhibitorinhibitorinhibit

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