Antifungal agent 44 

Antifungal agent 44 (compound 2A-5) is an antifungal agent, and shows excellent fungicidal activity superior to Kresoxim-methyl (HY-125776). Antifungal agent 44 shows fungicidal activity against Phytophthora capsici most remarkably, with an EC₅₀ value of about 5 μM^[1].

Antifungal agent 44 displays hyphal distortion, shrinkage, increased branching, and abnormal tip^[1].
Antifungal agent 44 (70 μM; 3 h) causes P. capsici zoospore fragmentation^[1].
Antifungal agent 44 (4.375-70 μM; 1 h) causes the death of P. capsici zoospores in a dose-dependent manner^[1].
Antifungal agent 44 (3 h) inhibits ATP production in P. capsici^[1].
Antifungal agent 44 (4.375 and 17.5 μM; 30 min) increases the intracellular ROS level of P. capsici in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

732.73

C₄₁H₅₁BrNO₄P

CO/N=C(C(OC)=O)\C1=C(COCCCCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=CC=C1.[Br-]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Liu X, et al. Mitochondrion-Targeted Triphenylphosphonium-Based Kresoxim-Methyl Analogues: Synthesis, Fungicidal Activity, and Action Mechanism Approach. J Agric Food Chem. 2022 Oct 12.  [Content Brief]