2. Anti-infection
  3. Fungal
  4. Antifungal agent 68

Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51.

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Antifungal agent 68 Chemical Structure

Antifungal agent 68 Chemical Structure

CAS No. : 2925307-53-3

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Antifungal agent 68 Related Antibodies

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Description

Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51[1].

Molecular Weight

414.93

Formula

C23H27ClN2O3
CAS No.
SMILES

CCCC1=CC=C(OCC(OCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(OC)=C1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Antifungal agent 68 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 682925307-53-3Antifungal agent68Antifungal agent-68FungalCYP-51Candida aurisCandida spp.ErgosterolEugenolNew azolesInhibitorinhibitorinhibit

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