1. Anti-infection
  2. Parasite
  3. Antileishmanial agent-14

Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM).

For research use only. We do not sell to patients.

Antileishmanial agent-14 Chemical Structure

Antileishmanial agent-14 Chemical Structure

CAS No. : 1638956-72-5

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Description

Antileishmanial agent-14 is a sulfuretin analog with potential activity against the parasite Leishmania donovani promastigotes (IC50=4.1 μM). Antileishmanial agent-14 also inhibits infection by L. donovani amastigotes (IC50=11.1 μM)[1].

In Vitro

Antileishmanial agent-14 (compound 2o) (25 μM, 50 μM) inhibits activity of L. donovani amastigotes with inhibitory rates of 116% and 115% at 25 μM and 50 μM, respectively[1].
Antileishmanial agent-14 decreases L. donovani amastigotes parasite number with IC50 of 4.6 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

431.91

Formula

C23H26ClNO5

CAS No.
SMILES

O=C1C2=CC=C(OCCN3CCCC3)C=C2O/C1=C\C4=C(C=CC(OC)=C4)OC.Cl

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Antileishmanial agent-14 Related Classifications

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Antileishmanial agent-14
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HY-149093
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